Colleton County, SC (WLTX) - Four children are dead and three other people are injured following a crash on Interstate 95 in Colleton County in the Lowcountry.

Officers say the collision happened Friday morning near mile marker 44, which is a few miles from the town of Yemassee. Investigators say a vehicle and a tractor-trailer collided at the location, and several people became trapped in the vehicle.

Investigators have not yet said the connection between all those who died and the three who were injured. The injured are receiving treatment at area hospitals.

The interstate in that area was shut down for several hours.