The mix of floodwaters and drilling operations has also spurred environmental and health concerns that industry and government officials say they are closely monitoring, and that activists have seized on as another demonstration of the dangers posed by hydraulic-fracturing.
Pictures and videos that cropped up on anti-fracking sites and in local news outlets in recent days show inundated oil pads, flooded wells, and, in some cases, overturned tanks and ruptured lines. Many were reportedly captured in Weld County, an area northeast of Denver and Boulder that was hit hard by the flooding.
With nearly 18,000 active wells, it's also a main drilling center in Colorado, a state that increasingly relies on hydraulic-fracturing for its energy production.
"Water pollution is the biggest concern," said Gary Wockner, the Colorado program director for the anti-fracking group Clean Water Action.
"Our biggest fear is that oil and gas hydrocarbons and hydrofracking chemicals will get into the water supply, and that the flooding will spread the pollution over a large swath of the landscape."
While industry representatives have downplayed what one executive called the"social media frenzy" of photos and videos due to lack of information, they have taken steps to mitigate concerns, including stopping the flow of oil at potentially affected wells, a process known as shutting in.
Doug Hock, the director of public relations for Encana Oil & Gas which operates a number of wells in the area, said that of the 1,241 wells Encana operates in the energy-heavy Denver-Julesburg Basin, 397 were shut in last week. Since then, 99 of those shut in have returned to production.
"We still have not found any spills of any reportable quantity, but cannot rule out future discoveries until we get to everything," Hock said Tuesday.
For their part, Colorado officials have been "aggressively assessing the impacts of the flood to oil and gas facilities," Colorado Department of Natural Resources spokesman Todd Hartman said in a statement.
Officials note that there's still limited information concerning the status of the area's oil and gas locations, but are warning about the potential health risks associated with hazardous materials in the flood water.
"The Colorado Department of Public Health and Environment is advising Coloradans that many contaminants, such as raw sewage, as well as potential releases of chemicals from homes, businesses and industry, may be contained in the floodwaters," Hartman said in his statement.
"People are encouraged to stay out of the water as much as possible."
Specialists in the hydraulic fracturing field offered mixed assessments of the situation.
"They're being overly cautious," said William Fleckenstein, the interim department head of petroleum engineering at the Colorado School of Mines, referring to the activists' concerns about flooded wells.
Most natural gas wells, Fleckenstein said, are designed to withstand large amounts of pressure, and to stay sealed under all conditions. Though he noted that it's hard to predict the potential damage posed posed to a well site by rushing water combined with debris.
"With just inundation -- unless the ground is structurally being damaged -- the wells should be in fairly good shape," he said.
"The biggest concern is open-wastewater pits," said Robert Jackson, a professor of environmental sciences at Duke University, who lead a study earlier this year linking fracking to water contamination. The hazardous fluid waste from hydraulic fracturing, also called flowback water, is sometimes stored in open-air pits that Jackson said can possibly overflow if inundated.
In Colorado though, according the the Colorado Oil and Gas Association, the wastewater is generally stored in holding and treatment tanks before disposal or reuse. A June 2012 Colorado Oil and Gas Conservation Commission presentationon regulating pits includes pictures of open-air pits in Weld County.
Colorado officials said that they are assessing the impact to open pits, but that generally there are fewer pits in the Wattenberg Field area where the floodwaters struck than in areas further east, which were mostly unaffected by the floods.
In response to a inquiry from CBSNews.com, CDNR's Hartman said: "It's important to remember what's in the pits, and their purpose. Pits are rarely used in hydraulic fracturing operations in northeastern Colorado. Fracturing and flowback fluids are held in storage tanks and then are either recycled or transported to a disposal well. The pits that are used during hydraulic fracturing store fresh water. It is also quite rare to have a drilling pit in the western part of the DJ Basin as companies have moved toward closed loop drilling as a way to reduce the size of their surface disturbance and in order to reuse the drilling fluids."
Jackson also said chemicals on inundated oil pads where drilling occurs could present a health and environmental concern, though Fleckenstein said regulations would have kept oil and gas companies from storing those chemicals in an unsafe manner.