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Tampa, Florida -- A jobs alert out of Tampa where nearly 400 people will soon be out of work.

Express Scripts, a national pharmacy benefit manager which has operations in Tampa, said it lost a big client and that's costing employees their jobs. Nationwide, the St. Louis-based company says it will have to cut 1,890 jobs.

"Over the past year we've had a reduction in the amount of prescriptions we manage. Part of that is because a client, United Healthcare. has decided to take its pharmacy benefit management business in house," said company spokesman Brian Henry.

Employees were notified this week. Henry says there should be no impact to patients filling prescriptions.

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